Dexamethasone in acute bacterial meningitis

Dexamethasone improved disability in acute bacterial meningitis.

and commentary also appear in ACP Journal Club. 86 Volume 8 May/June 2003 EBM Therapeutics www.evidence-basedmedicine.com group.bmj.com on October 26, 2017 Published by http://ebm.bmj.com/ Downloaded from

Role of dexamethasone in acute bacterial meningitis in adults.

OBJECTIVE To evaluate the role of dexamethasone as adjunctive therapy in adult acute bacterial meningitis (ABM) in two groups of patients treated with antibiotics alone or a combination of antibiotics and dexamethasone. DESIGN Systematic sampling interventional open cohort study. SETTING Department of Medicine (Medical Unit II), Jinnah Postgraduate Medical Centre, Karachi. PATIENTS Sixty ...

Dexamethasone and bacterial meningitis in Pakistan.

The objective of this study was to assess, in a developing country setting, the effect of dexamethasone therapy on bacterial meningitis outcomes. A prospective double blind placebo controlled trial was conducted in 89 children aged from 2 months to 12 years suffering from bacterial meningitis. Neurological, developmental, and hearing assessments were conducted at one, four, and 12 months after ...

Dexamethasone in Adults with Bacterial Meningitis

Dexamethasone in adults with bacterial meningitis.

BACKGROUND Mortality and morbidity rates are high among adults with acute bacterial meningitis, especially those with pneumococcal meningitis. In studies of bacterial meningitis in animals, adjuvant treatment with corticosteroids has beneficial effects. METHODS We conducted a prospective, randomized, double-blind, multicenter trial of adjuvant treatment with dexamethasone, as compared with pl...